Pigmented Villonodular Synovitis (PVNS) is a benign (non-cancerous) condition that occurs due to overgrowth of the synovium, the tissues that line the joints, or production of excess synovial fluid. A majority of PVNS cases occur in the knee. Treatment of PVNS commonly includes a synovectomy to remove the excess tissue and fluid.

A neurofibroma is a somewhat rare, benign (non-cancerous) soft-tissue tumor that can occur on any peripheral nerve. It presents as a small mass with mild to no symptoms. Surgical removal is a common treatment for nuerofibromas.

A schwannoma is a benign (non-cancerous), soft-tissue mass that presents on the outer, protective layer of a nerve, called the epineurium. To treat, a schwannoma can be marginally excised, meaning only the schwannoma is surgically removed, to spare or protect the nerve from excision.

Infantile Fibromatosis is a rare condition that involves the growth of a single or numerous benign (non-cancerous) tumors. It is often referred to as myofibromatosis, due to the abundance of fibrous and smooth muscle stoma. Infantile fibromatosis can affect the skin, muscles, soft-tissues, bones and rarely visceral organs.

Giant Cell Tumor (GCT) of Tendon Sheath is a benign, or non-cancerous, tumor that can emerge from the tendon sheath or synovium. It most commonly affects the fingers and hand and can be treated with surgical resection or removal of the mass.

Undifferentiated Pleomorphic Sarcoma (UPS) is a cancerous (malignant) soft-tissue tumor that most commonly affects the soft-tissues of the upper and lower extremities, however can occur anywhere.

Most common soft tissue cancer of the foot and ankle that arises from tendons, bursae or joints.

A cancerous soft tissue tumor that arises from the skeletal muscle. This condition is rare, yet one of the more common cancers seen in children.

Malignant Peripheral Nerve Sheath Tumor is a malignant (cancerous) tumor that occurs on the outer, protective covering of nerves.

Round Cell Liposarcoma is a malignant, or cancerous, soft-tissue sarcoma that most commonly occurs in the deep tissues of the thigh, or other extremities. It is fairly aggressive and has a greater potential for metastasis.

Pleomorphic liposarcoma is a malignant, or cancerous, soft-tissue tumor that most commonly occurs intramuscularly or subcutaneously. It is the least common subtype of liposarcomas, however treated similarly to other liposarcomas, including surgical resection or removal of the tumor.

Myxoid Liposarcoma is a malignant, or cancerous, soft-tissue sarcoma that most commonly occurs in the deep tissues of the thigh, or other extremities.

Dedifferentiated Liposarcoma is a malignant (cancerous), soft-tissue sarcoma that most commonly occurs in the retroperitoneum, or the area in the back of the abdomen. It is an atypical liposarcoma that can arise from a low-grade, well-differentiated liposarcoma that can progress overtime into a dedifferentiated liposarcoma. Treatment includes surgical resection or removal of the tumor.

Liposarcoma is a malignant (cancerous) soft-tissue tumor that most commonly affects the extremities or the abdomen. They are the second most common soft-tissue sarcoma.

Primary leiomyosarcoma of bone is a rare type of malignant bone tumor. It most commonly occurs in the area behind the tissue that lines the abdomen (the retroperitoneum) and the pelvis. Leiomyosarcoma is also a malignant tumor than can occur in soft-tissue.

This condition is a rare cancer from cells that make up the blood vessels.

Rare type of cancerous sarcoma that arises from the dermis of the skin.

Clear Cell Sarcoma is known as Melanoma of Soft Parts. It is a very rare and aggressive sarcoma.

Extremely rare cancerous tumor that arises from the endothelial cells of blood vessels and lymph vessels

Alveolar Soft Part Sarcoma is a rare, slow growing, cancerous tumor that most commonly occurs in the deep soft-tissues of the thigh. It is treated with surgical excision, or removal, and systemic treatments.

A very rare benign tumor composed of cartilage that grows from the surface of the bone. Cartilage is made of a tough, flexible, connective tissue found in many areas of the body and lines joint surfaces. The periosteal chondroma forms in the periosteum, a fibrous membrane made up of blood vessels and connective tissue that covers the bone. Also known as juxtacortical chondroma.

A small and noncancerous bone tumor where the cells in the tumor, called osteoblasts, make new bone. There is no risk of the disease spreading.

The most common benign tumor, which constitutes 35% of all benign bone tumors, and 10% of all bone tumors overall. It is an overgrowth of the bone that happens at the end of the bone near the growth plate. It is made up of both bone and cartilage.

A rare, noncancerous but aggressive tumor that produces bone. If left unchecked, it will continue to grow and destroy the bone. Surgical treatment is preferred. There is a high risk of recurring, or coming back, after removal.

Benign (noncancerous) and non-aggressive tumor that consists of fibrous tissue. Commonly discovered by chance during an X-Ray done for another reason, such as a sports injury. Usually there are no symptoms and it resolves by itself.

Giant Cell Tumors of Bone are benign but aggressive tumors that destroy bones and can invade soft tissues. They most commonly affect the femur, tibia, radius, sacrum and skull.

Fibrous dysplasia is not considered a tumor, but a developmental disorder of the bone. Commonly affected areas include the facial bones (craniofacial), femur, tibia, and ribs.

Eosinophilic Granuloma is a benign bone tumor that causes a disease that creates too many immune cells. They are not a cause of cancer or an abnormal mass of tissue (neoplasm). This may come from any site within any bone in the body.

Enchondromas are benign tumors that may weaken the bone. They most commonly affect the hands and feet, with the humerus and femur being common larger bones.

A Chondromyxoid Fibroma (CMF) is a slow-growing benign yet aggressive bone tumor or neoplasm. Surgery is the standard of treatment. It is important that it is removed because it can be spread to other body parts.

Chondroblastomas are a rare type of noncancerous (benign) bone tumor that begins in is made up of cartilage cells. Chondroblastomas grow at the ends of the body’s long bones (called the epiphysis) near the joints.

Aneurysmal Bone Cysts are benign aggressive tumors that destroy bone. They most commonly affect the spine and growth plates of the femur and tibia.

Undifferentiated Pleomorphic Sarcoma (UPS) is the second most common bone sarcoma in adults after chondrosarcoma. Previously known as Malignant Fibrous Histiocytoma (MFH), UPS gets its name because of the way it looks under a microscope (histology). Undifferentiated describes how the cells do not look like the body tissues in which they develop. Pleomorphic means the cells grow in different shapes and sizes.

Telangiectatic Osteosarcoma is a cancerous bone tumor that produces bone. This type of tumor occurs primarily in the bone of the femur, and humerus.

A Periosteal Osteosarcoma is a cancerous bone tumor. It comes from within the bone (intramedullary). It is a cancerous tumor, and can lead to bone destruction. It is a slow growing tumor that will not spread to other parts of the body in most cases.

A low-grade sarcoma (cancerous; malignant) lesion that occurs on the surface of long bones and arises from the outer layer of the periosteum.The periosteum is the coating on the surface of the bone.

Conventional Osteosarcoma is the most common cancerous bone tumor that produces bone. This type of tumor occurs primarily in the bone of the femur, and humerus.

The most common type of primary bone cancer. This condition is a type of bone marrow cancer arising from plasma cells that can cause tumors in the bone. Plasma cells are normal cells in the blood that make antibodies.

Also known as Multiple Myeloma when it affects multiple bones. It is called a plasmacytoma when it affects a single bone.

Hemangiopericytoma of the bone is a malignant tumor originating from the cells around tiny blood vessels called capillaries (called pericytes). It most commonly affects the pelvis, femur, spine, and humerus.

This condition is a rare cancerous tumor composed of cells that make up the blood vessels, called endothelial cells. It is primarily seen in the lungs.