Pigmented Villonodular Synovitis (PVNS) is a benign (non-cancerous) condition that occurs due to overgrowth of the synovium, the tissues that line the joints, or production of excess synovial fluid. A majority of PVNS cases occur in the knee. Treatment of PVNS commonly includes a synovectomy to remove the excess tissue and fluid.

A neurofibroma is a somewhat rare, benign (non-cancerous) soft-tissue tumor that can occur on any peripheral nerve. It presents as a small mass with mild to no symptoms. Surgical removal is a common treatment for nuerofibromas.

A schwannoma is a benign (non-cancerous), soft-tissue mass that presents on the outer, protective layer of a nerve, called the epineurium. To treat, a schwannoma can be marginally excised, meaning only the schwannoma is surgically removed, to spare or protect the nerve from excision.

Infantile Fibromatosis is a rare condition that involves the growth of a single or numerous benign (non-cancerous) tumors. It is often referred to as myofibromatosis, due to the abundance of fibrous and smooth muscle stoma. Infantile fibromatosis can affect the skin, muscles, soft-tissues, bones and rarely visceral organs.